Czech filmmaker Milos Forman's first American production stars Linnea Heacock as Jeannie Tyne, a runaway teenager. While she wanders aimlessly around New York, her suburban parents, Lynn (Lynn Carlin) and Larry (Buck Henry), desperately search for their missing daughter. Larry and his best friend, Tony (Tony Harvey), inaugurate a search, but their expedition is sidetracked by a drinking binge at a local bar. Meanwhile, Lynn and Tony's wife, Margot (Georgia Engel), begin discussing their sex lives. Jeannie does finally return home, to constant questioning by her parents about which drugs she has taken; later, after Lynn and Larry join a support group for the parents of runaway children, they turn around and get stoned on marijuana themselves during one of the group meetings, then lapse into a randy game of strip poker -- little realizing that their daughter is close at hand and within earshot. As a critically revered lampoon of late-'60s sensibilities, Taking Off is full of unknown Manhattan-based performers who became famous during the '70s and '80s, including Paul Benedict, Vincent Schiavelli, Allen Garfield, Audra Lindley, and, in fleeting roles as auditioning singers, Carly Simon, who performs Long Time Physical Effects, and Kathy Bates (billed as Bobo Bates), who performs Even the Horses Had Wings.