New York, 1961. Against the backdrop of a vibrant music scene and tumultuous cultural upheaval, enigmatic 19-year-old Bob Dylan (Timothée Chalamet) from Minnesota arrives with his guitar and revolutionary talent, destined to change the course of American music.

He forges intimate relationships with music icons of Greenwich Village such as Woody Guthrie (Scoot McNairy), Pete Seeger (Edward Norton) and Joan Baez (Monica Barbaro) on his meteoric rise, culminating in a groundbreaking and controversial performance that reverberates worldwide.